New results show that people with a specific version of the gene are less likely to develop severe COVID-19. Previous research has identified a specific group of genes, called OAS1 / 2/3 gene clusters, that are at risk for severe COVID-19.
A version of the gene in that cluster – passed through Neanderthals, appeared to protect against serious disease, reducing the risk by about 23%. Previous research was largely on people of European descent. According to a report published in Nature Genetics, researchers are now seeing a similar association of this genetic type with less severe COVID-19 in people of African descent.
“The fact that people of African descent had similar protections allowed us to identify the only type in DNA that actually protects against COVID19 infection.” Co-author Dr. Jennifer Huffman said in a statement.
The researchers said that the OAS genes are involved in a cascade of effects that help cells fight off the virus. Understanding these genes and their effects on the risks of Covid 19 could help in the development of future drugs, they added.
Less Delta Success with Moderna vs Pfizer / BioNTech
When the delta variant coronavirus was widespread in the United States, recipients of the modern mRNA vaccine (MRNA.O) were less likely to be successfully infected and less likely to be hospitalized than those receiving two doses of the mRNA vaccine from Pfizer. And Bioentech, a major study.
The researchers analyzed the medical records of more than 637,000 vaccine recipients who had not previously been infected with the virus and had not received a booster shot.
The latest infections have been steadily rising every month from July to November 2021, with higher rates in the Pfizer / BioNTech group, the JAMA reported on Thursday.
In November, there were 2.8 cases per thousand people vaccinated with Pfizer / Biotech injections, compared to 1.6 cases per modern vaccine recipient.